- WR = Wright Robinson College
- BV = Belle Vue Sports Village
- Arena = Manchester Arena
| Rd | |||||
| 1 | Away | 10 February – 6pm | Severn Stars | V | Manchester Thunder |
| 2 | BV | 19 February – 7pm | Manchester Thunder | V | Sirens |
| 3 | WR | 23 February – 7.30pm | Manchester Thunder | V | Team Northumbria |
| 4 | Away | 26 February – 7pm | Loughborough Lightning | V | Manchester Thunder |
| 5 | BV | 3 March – 5pm | Manchester Thunder | V | Celtic Dragons |
| 6 | Away | 9 March – 7.30pm | Team Bath | V | Manchester Thunder |
| 7 | WR | 16 March – 7.30pm | Manchester Thunder | V | benecoMavericks |
| 8 | BV | 21 April – 5pm | Manchester Thunder | V | Surrey Storm |
| 9 | Away | 27 April – 7pm | Wasps | V | Manchester Thunder |
| 10 | Away | 5 May – 2pm | Sirens | V | Manchester Thunder |
| 11 | BV | 7 May – 5pm | Manchester Thunder | V | Loughborough Lightning |
| 12 | Away | 12 May – 6pm | Team Northumbria | V | Manchester Thunder |
| 13 | WR | 19 May – 5pm | Manchester Thunder | V | Severn Stars |
| 14 | Away | 25 May – 7pm | Celtic Dragons | V | Manchester Thunder |
| 15 | Arena | 2 June – 2.15pm | Manchester Thunder | V | Wasps |
| 16 | Away | 9 June – 6pm | benecoMavericks | V | Manchester Thunder |
| Rearranged | WR | 11 June – 7pm | Manchester Thunder | V | Celtic Dragons |
| 17 | Away | 16 June – 6pm | Surrey Storm | V | Manchester Thunder |
| 18 | WR | 23 June – 5pm | Manchester Thunder | V | Team Bath |